In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 7051-16-3 as follows. Computed Properties of C8H9ClO2
Place 1-chloro-3,5-dimethoxybenzene (70 g, 406 mmol) and pyridine hydrochloride (468 g, 4055 mmol) in a round bottom flask.And then refluxed and stirred at 200 C for 24 hours. When the reaction is complete,The resultant was cooled to room temperature and then poured slowly into distilled water,And the mixture was stirred for 1 hour.The solids were filtered to obtain 51.6 g (88%) of Intermediate 10 (Int-10).
According to the analysis of related databases, 7051-16-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Samsung Sdi Co Ltd; Kim, Changwoo; Lee, Seungjae; Kim, Hyung Sun; Ryu, Dong Wan; Shin, Chang Ju; Jang, Kipo; Jung, Sung Hyun; Jung, Juyeon; Chu, Handong; (79 pag.)TW2019/30299; (2019); A;,
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