Reference of 2687-12-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2687-12-9, name is Cinnamyl chloride belongs to chlorides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
In a 25 mL high pressure dad, Palladium acetylacetonate (15.2 mg, 0.05 mmol) was added, Tetrabutylammonium chloride (277.9 mg, 1.0 mmol), Potassium fluoride (58.lmg, 1.0 [eta] [eta] & lt; 1 & gt;), And a stirring magnet was charged. After nitrogen substitution three times, Add cinnamyl chloride to high pressure dad (152.6 mg, 1.0 mmol,), Tetrahydrofuran (2 mL), Boronic acid pinacol ester (168. Omg, 1.O mmol), The charging port and the charging port are then closed. Carbon dioxide high pressure cylinders are connected to one atmosphere of carbon dioxide gas. The autoclave was stirred in a 90 C oil bath for 24 hours. After completion of the reaction, Slowly release the excess carbon dioxide, The reaction solution was transferred onto a 30 cm high silica gel column, Using petroleum ether: ethyl acetate as a developing solvent of 100: 1 column, The pure product was isolated, The yield of this reaction was 95%.
The synthetic route of Cinnamyl chloride has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Dalian University of Technology; Feng, XiuJuan; Sun, Jian; Bao, Ming; Yu, Xiaojiang; Zhang, Sheng; (25 pag.)CN105777463; (2016); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics