Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 27139-97-5, name is 2-Bromo-4-chloro-1-methylbenzene, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C7H6BrCl
2-Bromo-4-chlorobenzylbromide (5b). To the bromoderivative (6.71 g, 32.68 mmol) (4) dissolved in CCl4 were added N-bromosuccinimide (NBS) (5.82 g, 32.68 mmol), a,a’-azoisobutyronitrile (AIBN) (107.2 mg, 0.65 mmol) and after heating at reflux for 4 hours, the reaction mix- ture was cooled and filtered on Gooch. The filtrate was washed with aqueous sodium thiosulphate solution and then the organic phase was anhydrified on anhydrous sodium sulphate and the solvent evapo- rated. The crude reaction product was purified by flash chromatogra- phy, using n-hexane as the eluent. 6.00 g of product (5b) are thus obtained as a colourless oil with a yield of 64%. ?H NMR (CDCIs) 8 7.58 (d, 1H, J = 1.75 Hz), 7.38 (d, 1H, J = 8.51 Hz), 7.28 (m, 1H), 4.55 (s, 2H); MS m/z 284 (M+), 205 (100), 169,124, 89; Anal. (C7H5Br2CI) C, H, N compliant with the expected structure.
According to the analysis of related databases, 27139-97-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.; MINETTI, Patrizia; WO2005/97797; (2005); A2;,
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