Reference of 626-43-7, These common heterocyclic compound, 626-43-7, name is 3,5-Dichloroaniline, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
EXAMPLE 5; Preparation of 1,3,5-triaminobenzene from 3,5-dichloroaniline, hydrolysis with hydrochloric acid of the 1,3,5-triaminobenzene to phloroglucinol; A pressurized vessel is charged with 30 g (18.6 mmol) of 3.5-dichloroaniline and 1.8 g of copper iodide in 160 ml of 28% aqueous ammonia. The mixture is heated at 190 C. and under a pressure of 40 bars for 24 h. The contents of the vessel are poured into 200 ml of water and then the excess ammonia is removed. Then 56 g of 10 N hydrochloric acid are added and the mixture is heated at 110 C. for 20 h. Following filtration, the solution is cooled in an ice bath until the phloroglucinol precipitates. The precipitate obtained is subsequently recrystallized from 400 ml of a water-methanol (95 V-5 V) mixture.
Statistics shows that 3,5-Dichloroaniline is playing an increasingly important role. we look forward to future research findings about 626-43-7.
Reference:
Patent; PHV ANALYITIC; US2005/165256; (2005); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics