6579-54-0, name is 2,6-Dichlorobenzenesulfonyl chloride, belongs to chlorides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. SDS of cas: 6579-54-0
Taking 245 mg 2,6-dichlorobenzenesulfonyl chloride dissolved into 20 ml anhydrous methanol, stirring 20 min, add m-phenylenediamine 450 mg and triethylamine 3 ml, in 70 C under stirring 12 h cooling, methanol, water, extracted with ethyl acetate three times, the combined organic phase, water washing, water-free MgSO4Drying, evaporating the solvent, purification with silica gel column chromatography, eluting agent volume ratio: AcOEt: petroleum ether=1:4, to obtain white solid N,N’-bis(2,6-dichlorobenzenesulfonyl)m-phenylenediamine 515 mg, yield 98%.
The synthetic route of 6579-54-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jishou University; Xiao Zhuping; Ni Weiwei; Fu Zijuan; Yi Juan; Zhou Tianli; (21 pag.)CN109096156; (2018); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics